Chlorthalidone Blood Pressure Pills Recalled Again: Check Your Bottle

Chlorthalidone is a prescription diuretic, sometimes called a “water pill.” It is commonly used to treat high blood pressure and can also be used to reduce excess fluid associated with certain medical conditions.

For someone taking it to control blood pressure, getting the intended dose consistently matters.

The September 2026 recall involves:

• Chlorthalidone Tablets, USP, 25 mg
• 100 tablets per bottle
• NDC: 64980-599-01
• Lot/batch: RISA24002
• Expiration date: April 2027
• 13,567 bottles
• Distributed nationwide
• Manufactured by Inventia Healthcare Limited
• Distributed in the United States by Rising Pharma Holdings, Inc.

The manufacturer initiated the recall on September 3, 2026. The FDA classified it as a Class II recall on September 17.

The most important thing is the lot number.

If your bottle says RISA24002 and has an expiration date of 04/2027, contact your pharmacist or healthcare provider for instructions about getting a replacement.

If your pharmacy transferred the medication into an orange prescription bottle, the original lot number may not appear on the label. In that case, your pharmacist can determine which lot you received.

This sounds more alarming than it necessarily is.

Before a tablet is approved and distributed, manufacturers test how it breaks down and releases its active ingredient. Dissolution testing helps determine whether the medicine is releasing the drug as expected.

A failure means the affected tablets did not meet the required dissolution specifications. That could affect how consistently the medication releases its active ingredient and therefore how predictably it works.

It does not mean that every tablet contains the wrong amount of medication, or that everyone who took one will be harmed. A laboratory dissolution failure cannot tell us exactly how much medication any individual patient absorbed.

This isn't the first chlorthalidone recall this year.

In June, Inventia recalled approximately 11,460 bottles of 25 mg chlorthalidone for the same reason: failed dissolution specifications.

That earlier recall involved lots RISA24001 and RISB24002, both with an April 2027 expiration date. The September recall involves the additional RISA24002 lot. Together, the two recalls affect more than 25,000 bottles.

The FDA uses three main recall classifications.

Class I is the most serious and involves a reasonable probability of serious health consequences or death.

Class II means use of the product may cause temporary or medically reversible health consequences, or that the probability of serious health consequences is considered remote.

Class III means use of the product is not likely to cause adverse health consequences.

This chlorthalidone recall is Class II.

That is important—but it doesn't mean the FDA believes everyone taking the recalled tablets is in immediate danger.

This may be the most important part of the alert.

If you discover that you have the recalled lot, don't simply stop taking your blood-pressure medication without talking to your pharmacist or healthcare provider.

The FDA specifically notes that with Class II and III drug recalls, patients can generally continue taking the medicine unless the manufacturer or FDA provides different instructions. In some situations, abruptly stopping a medication can itself create a health risk.

Instead:

• Check your bottle.
• If the lot is RISA24002, contact your pharmacist or prescriber.
• Ask about obtaining an unrecalled replacement supply.
• Follow their instructions about what to do with the recalled medication.
• Continue monitoring your blood pressure as you normally would, unless your healthcare professional tells you otherwise.

Blood pressure often doesn't give you any warning when it rises.

That's one reason medications such as chlorthalidone can be important even when you feel perfectly fine. If a medication isn't performing as intended, the problem may not announce itself with an obvious symptom.

The purpose of a recall is to catch a potential quality problem before it becomes a bigger problem.

So this isn't a reason to panic.

It's a reason to check the bottle.

If you take chlorthalidone, check your bottle for lot RISA24002 and an April 2027 expiration date. If it matches, don't stop the medication on your own—contact your pharmacist or healthcare provider about getting a replacement.